Boys more at risk from Pfizer jab side-effect than Covid, suggests study

Saul Faust, professor of paediatric immunology and infectious diseases at the University of Southampton, who was not involved in the work, said the findings appeared to justify the cautious approach taken on teenage vaccines by the UK’s Joint Committee on Vaccines and Immunisation.

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The overwhelming majority of myocarditis appears after the second dose of vaccine, so offering single shots could protect children while reducing their risk of the side effect even further.

“While myocarditis after vaccination is exceptionally rare, we may be able to change the first or second doses or combine vaccines differently to avoid the risk at all, once we understand the physiology better,” said Prof Faust. “On balance, there is no urgency to immunise children from a medical perspective, although if schools are unable to maintain education for the vast majority at all times, the overall balance could shift. If my two teenage children are offered the vaccine by the NHS my GP wife and I will have no hesitation in allowing them to receive the vaccine.”

Prof Adam Finn, a member of JCVI at the University of Bristol, said: “I stand by the JCVI advice, which is not to go ahead at this time with vaccinating healthy 12 to 15-year-olds on health outcome risk-benefit grounds given the current uncertainty – as there is a small but plausible risk that rare harms could turn out to outweigh modest benefits.”

The MHRA said it has been closely monitoring all available data on the potential risk of myocarditis and pericarditis following Covid-19 vaccination. “We have concluded that the Covid-19 vaccines made by Pfizer/BioNTech and Moderna may be linked with a small increase in the risk of these very rare conditions. The cases tended to be mild and the vast majority recovered with simple treatment and rest,” they added.

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The spokesperson said the latest study had been considered by the government’s independent advisory body, the Covid-19 vaccines benefit risk expert working group, which found that the interpretation of the findings was limited by the fact that the study did not take into account differences in treatment practices when comparing hospitalisation rates between Covid-19 infections and myocarditis and pericarditis presenting post-vaccination, and there was no assessment of severity and duration of illness after admission.

“Safety monitoring strategies are in place for individuals under 18 years, including monitoring myocarditis and pericarditis occurring post-vaccination and the long term outcomes with these events. The MHRA continues to keep the safety of Covid-19 vaccines under close and continual review,” the spokesperson added.

Source: The Guardian