VACCINES & GRAPHENE – 1. Dangerous & Mysterious Nanoparticles inside mRNA Serum. “Toxicology NOT Thoroughly Investigated” Pfizer Wrote

VACCINES & GRAPHENE – 1. Dangerous & Mysterious Nanoparticles inside mRNA Serum. “Toxicology NOT Thoroughly Investigated” Pfizer Wrote

525.517 Views
1 – CONFLICTS OF INTERESTS IN A TREMENDOUS PLOT
2 – COMIRNATY: “TOXICOLOGICAL PROPERTIES NOT THOROUGHLY INVESTIGATED”
3 – PFIZER’S SECRET “PF” NANOPARTICLES: EXCELLENT GRAPHENE LAIR
4 – THE RISK OF BIOTECHNOLOGICAL COMPOUNDS
5 – GRAPHENE NANOPARTICLES FOR VACCINES AGAINST SARS-COV-2
6 – GRAPHENE OXIDE INSIDE LIPID MEMBRANES
7 – “CELL DAMAGE FROM THE SHARP EDGES OF GRAPHENE”

by Fabio Giuseppe Carlo Carisio

VERSIONE ORIGINALE IN ITALIANO

Investigation originally published in Italian by Gospa News on February, 2, 2022

«Specific hazards arising from the chemical: Fine particles (such as mists) may fuel fires/explosions. Hazardous combustion products: Formation of toxic gases is possible during heating or fire. As a precautionary measure, keep away from heat sources and electrostatic discharge, and from strong oxidizers».

Paragraph 5.2 of the Safety Data Sheet (Source -1 at the end of the article) of Pfizer-BioNTech COVID-19 Vaccine reads this in relation to the “Special hazards arising from the substance or mixture” which falls within the Chemical family of “Lipid Nanoparticles containing PF-07305885 (BNT162b2) and Lipids”.

This would be enough for a sane human being to immediately shout “Vade Retro… Gates!”.

The first page of the Pfizer-Biontech Safety Data Sheet on Comirnaty – link below

At the mere thought of this messenger RNA-based compound built by the American Pfizer with the German Biontech (funded by Bill Gates), as part of a broader international partnership that in a previous article we called the “Vaccines Triad” because the British GlaxoSmithKline (GSK), managed by a director of Microsoft Corporation, and the other American Novavax, a newcomer to the group with recombinant proteins also conveyed by nanoparticles, also converge alongside the “official” Pfizer-Biontech duo.

LA TRIADE DEI VACCINI. Intrighi Miliardari tra GSK, PFIZER, NOVAVAX con Lobby Sioniste, Gates, Biden & BoJo

Both Comirnaty and Spikevax (from Moderna) «consisted of N1-methyl-pseudouridine-modified mRNA encoding the SARS-COVID-19 Spike protein and were delivered with a lipid nanoparticle (LNP) formulation. Because the delivery problem of ribonucleic acids had been known for decades, the success of LNPs was quickly hailed by many as the unsung hero of COVID-19 mRNA vaccines».

This was explained (Source 2) by Hironori Adachi and Yi-Tao Yu of the Department of Biochemistry and Biophysics of the University of Rochester Medical Center, New York (USA) together with Pedro Morais of ProQR Therapeutics in Leiden (Netherlands) to highlight the importance of pseudouridine, without losing the precious contribution of the nanoparticles that are at the center of this report.

Huge Mystery: After Secret Meeting with Cops Two Anti-VAX Scientists Died! Hit by SARS-Cov-2 BioWeapon

But in the precious document of the Big Pharma of New York recently revised (December 7, 2021) which we came into possession of thanks to Divine Providence, we read many other very arcane things both in relation to the composition and to the toxicity / danger for the same researchers of Pfizer and Biontech committed to elaborating the doses of the experimental gene serum.

In it, the “miraculous” stabilization of the lipid nanoparticles of the shady biotechnologies could have been obtained with the inclusion of the highly contested “graphene oxide”. This material is the subject of controversy between scientists and bloggers but also of a secret meeting after which two of them died, the biologist Franco Trinca and the influencer / pharmacologist Domenico Biscardi.

In fact, Comirnaty is no longer experimental only in the USA: where it has received full approval from the Food and Drug Administration (for over 16 yo only) although amidst the objections of the British Medical Journal and the lawyer Robert F. Kennedy jr. for the failure to convene the independent advisory committee for the analysis of company pharmacovigilance data provided by Big Pharma of New York.

1 – CONFLICTS OF INTERESTS IN A TREMENDOUS PLOT

The suspicion that graphene oxide (GO) nanoparticles have been secretly inserted into the Pfizer vaccine has been hovering for months now, as discovered by the Spanish chemist Paulo Campra thanks to his electron microscope aimed at the contents of some vials of a declared batches.

In this investigation we will try to demonstrate how this was not only possible but also very probable due to macroscopic conflicts of interest that gravitate around the American pharmaceutical company Pfizer:

WUHAN-GATES – 32. Bill III, Vaccines’ Global Emperor. Crowned by Big Pharma’s Cartel within Gates Foundation’s Deal

By a monstrous coincidence on September 12, 2019, a few weeks before the “official” outbreak of the pandemic in China, the European Commission met in Brussels in the presence of the Director General of the World Health Organization, Tedros Adhanom Gebreyesus (puppet of Gates, the first WHO financier) and other world political and health authorities to discuss a global immunization project proposed by the directors of 4 NGOs also founded by Gates, which also included a Facebook executive and, above all, the only representative of Big Pharma, Nanette Cocero in charge of the vaccine branch of Pfizer Biopharmaceuticals Group !!!

By another sinister coincidence a month earlier, the Event 201 exercise funded by Gates and Klaus Schwab (WEF and Great Reset) was held in New York in which the Covid-19 emergency already prophesied by Bill III (he really defines himself …) but also by a great protagonist of this “simulation”: the lawyer Avril Haines, expert in bacteriological weapons and deputy director of US counterintelligence during the Obama-Biden administration just when the biolabs of Chapel Hill of North Carolina University carried out the very dangerous experiments on the chimeric SARS viruses of 2003 with enhanced viral load (Gain-of-Function).

Haines was then appointed by Biden National Director of US Intelligence and tried, unsuccessfully due to opposition from two 007 agencies, to support the natural origin of SARS-Cov-2.

WUHAN-GATES – 26. SARS-2 Bio-Weapon & Gold Vaccines. From CIA-WHO Tests funded by Gates to EU Summit with Pfizer, Biden’s sponsor, before Pandemic!

These highly risky tests were conducted under the supervision of Anthony Fauci, director of the NIAID (National Institute for Infectious Diseases) and White House pandemic emergency consultant, thanks to an HIV-infected SARS plasmid (traces of which have been found in SARS -Cov-2 by at least 12 scientists) provided by the Chinese bat-woman Shi Zhengli-Li, director of the Infectious Diseases Center of the Wuhan Institute Center, developed in other risky research thanks to the 2004 funding of the Episars Project of the European Commission chaired by Romano Prodi,  friend of George Soros (sponsor of the American Democrats), and future Italian premier of the Democratic Party, among whom are the main suspects of complicity with the Obama-Biden administration in the plot behind the pandemic.

Those who have carefully read the 53 investigations of the WuhanGates cycle (50 already translated into English and 27 summarized in the book of the same name for now only in Italian) know these passages by heart and may even consider them idle. If we weren’t about to reveal the latest sensational coincidence.

WUHAN-GATES – 50. The Italian Boss of Obama’s Coronavirus. Ukraine Laboratories Funded by former CIA Director Leon Panetta

 

In the previous investigation on “Vaccines & Graphene (at the moment in Italian only, readable with machine translation)” we highlighted various researches for the use of graphene oxide in the biomedical field and also in vaccines. We found that some had been funded by “Horizon 2020, the EU’s largest research and innovation program ever.” Almost 77 billion euros of loans are available in seven years (from 2014 to 2020).

During the meticulous checks for the elaboration of this reportage we discovered that GRAPHENE FLAGSHIP, with a budget of 1 billion euros, is one of the large-scale initiatives organized by the Future and Emerging Technologies program, together with the Human Brain Project and Quantum Technologies Flagship.

It is owned by the European Union and was designed in 2009 by the European Commission which made it operational in 2013 to implement major scientific and technological challenges.

Since 2014, just as experiments on SARS viruses were being carried out in China and the USA, it was included in the larger Horizon project which for the umpteenth, perverse and diabolical coincidence had an expiry in 2020, the year of the pandemic and of the new mRNA vaccines with nanoparticles.

WUHAN-GATES 43. SARS-BioWeapon & Shady Conspirators of China-US-WHO-EU Pandemic. Clinton & the Exterminator of Tiananmen

2 – COMIRNATY: “TOXICOLOGICAL PROPERTIES NOT THOROUGHLY INVESTIGATED”

The toxicity / dangerousness of Comirnaty not yet well classified in the work environment (we will see in detail on the basis of which international safety standards) leads to presumed similar risks also for end users: including minimally the administrators (nurses and doctors) and in large part the inoculated.

«Toxicological properties have not been thoroughly investigated. The following information is available for the individual ingredients – is Pfizer’s puzzling admission inside the Safety Sheet – In the event of accidental injection, an allergic reaction may occur. If an allergic reaction occurs, the worker should be removed to the nearest emergency room and the appropriate therapy instituted. Based on clinical trials in humans, possible adverse effects following intravenous exposure to this compound may include: injection site pain, muscle pain, headache, fever, chills, tiredness, joint pain, abnormal redness of skin (erythema), and sleep disturbances. Serious allergic reactions, including anaphylaxis, have been reported».

Reading Section 11 of Comirnaty’s Safety Data Sheet, one wonders how this drug product could have obtained definitive approval from the FDA if not by virtue of that “UNVEILED CORRUPTION” publicly declared by Kennedy on behalf of the Children’s Health Defense association.

British Medical Journal Contested FDA for “Political Decision” on Full Approval of Pfizer Vaccine without Public Discussion of Data

And it is even more legitimate to ask with what courage the US regulatory body has urged the pharmaceutical multinational to immediately submit the request for authorization for emergency use even for children under 5 and infants of 6 months.

«Pfizer Inc believes that the information contained in this Safety Data Sheet is accurate, and while it is provided in good faith, it is without warranty of any kind, expressed or implied. If data for a hazard are not included in this document there is no known information at this time».

With this final sentence of the document, the New York-based Big Pharma emulates Pontius Pilate and washes his hands of it for the consequences that those who sign informed consent will suffer under the intimidation of losing their jobs or other fundamental social rights.

“Vaccines Kill above all Young Males”. Chilling Letter by 73 British Doctors Tweeted by Nobel prize M. Lewitt

In fact, it has already freed itself from any legal responsibility in relation to the 1,223 deaths that occurred in the first phase of massive vaccination and treacherously concealed.

But also of the tens of thousands of deaths already reported for suspected adverse reactions to pharmacovigilance platforms in the USA (VAERS), in the European Union (Eudravigilance) and in the United Kingdom (UKHSA), as well as the hundreds of Italian victims of the “Listen to Me Committee” and dozens of Americans already monitored by the National Institute of Health for post-vaccine symptoms similar to Long-Covid disorders.

“Coronavirus Vaccines may Cause Long Covid–like Health Problems” Science wrote

In the light of these first analyzes, discrediting, marginalizing or deriding a NO CAVIA or AntiVAX becomes comparable to a blasphemy against Humanity and God himself who created it.

This is why the careful analysis of this document from both a pharmacological and legal point of view is of enormous importance: because it could hide a further colossal motivation to induce a human being to refuse vaccination with Comirnaty (to begin with …) and others similar gene sera (Moderna with messenger Rna and AstraZeneca with DNA modified with adenoviral vector).

WUHAN-GATES – 48. Moderna Vaccine Patented 9 Months Before Pandemic. Thanks to the Fauci-Baric’ Manmade SARS Viruses

From this Safety Sheet, well-founded health justifications for refusal emerge that go far beyond those based on the much vaunted “human rights” sanctioned by the Nuremberg Code which prohibits trials under duress, and Article 7.3.1 of the Resolution with which the Council of Europe (CoE, not to be confided with the Council of the European Union) on 27 January 2021 wanted to “ensure that citizens are informed that vaccination is NOT mandatory and that no one is politically, socially or otherwise subjected to pressure to get vaccinated, if you don’t want it ”

3 – PFIZER’S SECRET “PF” NANOPARTICLES: EXCELLENT GRAPHENE LAIR

Now the article will necessarily become very technical. I therefore hope to be able to expose a synthesis of the crucial puzzles hovering as nightmare spectra on the mRNA sera, of which we have already highlighted the danger connected to prions as denounced by Professor Luc Montagnier, virologist winner of the Nobel Prize for the discovery. of HIV in 2008 and a great vaccine expert.

We have titled this investigation “Vaccines & Graphene” because the suspicion that this mineral extractable in the laboratory from graphite crystals has been inserted for experimental purposes in the gene sera is gradually taking on a great consistency in the face of our initial skepticism, especially in the light of two previous reportages.

VACCINI: ALLARME PRIONI “MUCCA PAZZA”. Montagnier “21 Morti dopo Dosi mRNA”. 5 Studi su Spike-SARS2 e Degenerazione Cerebrale

“Graphene is a thin” sheet “, the thickness of an atom, made up entirely of carbon atoms, bound together by very strong interatomic bonds. Carbon atoms are bonded by three of their four valence electrons, i.e. the outermost electrons of an atom, which form chemical bonds with other atoms. The fourth valence electron, left free, allows these “sheets” to bind to other layers of graphene, forming graphite. The latter, therefore, is nothing more than a block of several layers of graphene stacked, and linked together by weak intermolecular bonds, called Van der Waals forces, which are easily broken ” explains Andrea Savino in an article on ScienceCue in relation to the new uses of this material.

The presence of graphene oxide (GO) in the Comirnaty serum was reported by the Spanish chemist Pablo Campra, professor and researcher at the University of Almeria, who analyzed the contents of some vials and, after encountering opposition from the biological world of the same academy, in November 2021 published the final version of its analysis confirming that it has identified with certainty at least 8 graphene oxide nanoparticles among a total of 28 highly suspicious for the two-dimensional (2D) shape of this carbon allotrope.

VACCINI & GRAFENE – 1. Nel Comirnaty di Pfizer-Biontech trovate 8 Nanoparticelle in Spagna. Smentita Sospetta su AstraZeneca dall’Argentina

The Spanish chemist then launched an appeal: «We ask independent researchers, without conflicts of interest or coercion on the part of any institution, to carry out a broader counter-analysis of these products to obtain a more detailed knowledge of the composition and the potential risk for the health of these experimental drugs (in European Union’s countries but not more in US as we explained before – ed), remembering that the graphene materials have a potential toxicity to humans and its presence has not been declared in any authorization for emergency use».

Well, precisely in the Pfizer document it would be possible to identify the “lair” where the GO could be hidden.

In the FDA full Pfzer-BioNTech Fact Sheet (Source 3) they are listed: «Nanolipids, or tiny fat molecules, protect the mRNA and provide a “greasy” exterior that helps the mRNA slide inside cells. Nanolipid components in the Pfzer-BioNTech vaccine include: ((4-hydroxybutyl)azanediyl)bis(hexane-6,1- diyl)bis(2-hexyldecanoate), 2 [(polyethylene glycol)-2000]- N,N-ditetradecylacetamide, 1,2-distearoyl-sn-glycero-3- phosphocholine, and cholesterol».

“Heart Attacks Risk For Covid Vaccinated Pilots, Must Not Fly”. US Air Force Medical Officer Swore: “Toxic Substances in Sera”

The high toxicity of some of these substances has already been reported by Lieutenant Colonel Theresa Long, a surgeon in the US Air Force and medical director of the 1st Aviation Brigade Fort Rucker, Alabama. But we talk about these dangerous lipids in other articles on Novavax vaccine…

However, the real composition of the «lipid nanoparticles containing PF-07305885 (BNT162b2) and lipids» which represent the “chemical texture” of the Comirnaty gene serum remains shrouded in mystery.

While the PF-07305885 deriving from the Biontech patent BNT162b2 and therefore inherent to the active ingredient of messenger RNA is mentioned, the nature of the main compound PF-07302048 that encompasses it is not disclosed.

However, both are included in a V-OEB chemical classification which, as far as we know, was used for the first time in laboratory safety for Pfizer’s vaccine against Covid-19.

4 – THE RISK OF BIOTECHNOLOGICAL COMPOUNDS

«The Vaccines Occupational Exposure Band (V-OEB) is a classification that has been assigned to biotechnology-based vaccines and antigen components. Risk assessments should be performed to assess potential exposures and determine appropriate controls» we further read in the Pfizer Safety Sheet which, it should be remembered, only concerns the impact of the compound and the ingredients treated on laboratory workers.

Two pages of the Pfizer-Biontech Safety Sheet from which the two elements of a very new and indefinite toxicological classification emerge

If we read a similar previous document, updated on November 16, 2020 (Source 4), it appears that the V-OEB denomination did not yet exist.

In relation to the two secret components “PF” it was in fact written: “The range of biotherapeutic occupational exposure (B-OEB) is an interval of the acceptable daily quantity (ADI), based on the risk data available with the application of appropriate security. Engineering control measures need to be used to bring exposures into the relevant B-OEB; it is necessary to conduct additional administrative controls and use personal protective equipment to achieve exposure control down to the lower part of the band ‘.

WUHAN-GATES – 46. “SARS-COV-2 Designed Bioweapon. Toxic structure May be Replicated in Vaccines”. US Army Ret. Colonel said

To make even a layman understand the high level of danger of such laboratory work, just look for a quick explanation on Wikipedia on the meaning of EOB.

The purpose of the classification system of the OEB, Occupational Exposure Band better translatable into Italian as “professional” is to separate substances into different categories of danger when the available data are sufficient to do so, but inadequate to establish an Occupational Exposure Limit (OEL).

Occupational exposure band, also known as risk band, is a process aimed at quickly and accurately assigning chemicals to specific categories (bands), each corresponding to a range of exposure concentrations designed to protect the health of workers. These bands are assigned based on the toxicological potency of a chemical substance and the adverse health effects associated with exposure to the chemical substance.

The occupational exposure band has been used by the pharmaceutical industry and some major chemical companies over the past decades to establish exposure control limits or ranges for new or existing chemicals that do not have formal OELs.

EXCLUSIVE: Pfizer Paper confirms Genic Experiments on 5yo Kids. “Myocarditis Risks by Vaccines, Little Data… We”ll Study After FDA Authorization”

Unfortunately, however, the dangerousness / toxicology of the compound, having not been thoroughly studied as Pfizer herself states with the same candor with which it admitted that she had no data on myocarditis in children under 12, remains totally unknown in relation to multiple reactions (for example Paragraph 9 – Physical and Chemical Poperties) where there is an infinite series of “not data avaliable”, even in the voices on the solubility, flammability and self-ignition of the vaccine!

From these scientific evidences an immediate and disturbing question arises: why should I inoculate in my human body an artificial biochemical substance whose real toxicological impact on the workers themselves is unknown, despite they are also protected by any kind of biosecurity protection (gloves, goggles , masks, suits, etc.)?

5 – GRAPHENE NANOPARTICLES FOR VACCINES AGAINST SARS-COV-2

We gladly give up the burden of responding to the American president Joseph Biden, the Italian president Sergio Mattarella and the premier Mario Draghi who are doing everything to impose massive vaccination despite world-renowned scientists having predicted the danger during a pandemic (Luc Montagnier, Geert Vanden Bosshe, Laura Bolgan, Franco Trinca) coming to compare it to “a weapon of mass destruction” for the more infectious and vaccine-resistant variants that it can cause, as has been the case.

“Mass Vaccination during a Pandemic can Promote Variants more Infectious”. Montagnier, Vanden Bossche (ex Expert of Gates’ NGO) and Trinca said

But let’s continue with the “toxicological” X-ray of the gene serum of Big Pharma of New York which in paragraph 3, at the bottom of the percentage of the individual components, writes «Ingredient(s) indicated as hazardous have been assessed under standards for workplace safety. In accordance with 29 CFR 1910.1200, the exact percentage composition of this mixture has been withheld as a trade secret» even if the only one labeled with the “hazardous” profile is Potassium Chloride (KCl), of Acute Tox 5 scale.

Although this salt is quite safe when given orally, it is lethal at 75-150 mg / kg IV. The injection of a lethal dose of KCl causes death from cardiac arrest: it is in fact used in combination with other enlargers for capital punishment in some states.

664 Reports of Myocarditis in 5- to 17-Year-Olds After COVID Shots, VAERS Data Show in the US

But the dose used in Comirnaty would be minimal and therefore only dangerous for the workers who tulip it to assemble the product. Therefore we do not digress on sudden illnesses due to cardiological attacks even among young people, otherwise we would not finish today’s topic. We will be back soon.

Also in the Additional Information of section 3, under the table on “Estimated Acute Toxicities”, it is specified «In accordance with 29 CFR 1910.1200, the exact percentage composition of this mixture has been withheld as a trade secret».

Faced with this other statement in the Pfizer Safety Sheet, the mysteries are magnified and make us return to the mysterious lipid nanoparticles. Which we would have difficulty talking about if we hadn’t published the previous survey “Vaccines & Graphene – 2. Nanoparticles speak Italian. Awarded Studio of the famous Capua and of the young Delogu “.

An example of the graphene oxide sheets dispersed in the syringe liquid and ready to be inoculated into a human being according to the experimental research of Dr. Lucia Gemma Delogu mentioned by the Graphene Flagship project of the European Union – Source 5

«Notably, only the amino-functionalized GO was able to induce a specific monocytoid dendritic cell (mDCs) and monocyte activation skewed toward a T helper (Th)-1/M1 response. These findings are starting points for the development of nanoscale platforms in medicine as immunotherapeutics, vaccine carrier, or nanoadjuvant tools».

This is what was written in a 2017 study (source 9), together with other European researchers, by Dr. Lucia Gemma Delogu, a young Sardinian scientist from the Department of Biomedical Sciences of the University of Padua, who has become the world reference point for Graphene Flagship, the association international which, as explained in the introductory part, is monitoring the potential of this new material derived from carbon on the initiative of the European Commission.

VACCINI & GRAFENE – 2. LE NANOPARTICELLE PARLANO ITALIANO. Premiato Studio della famosa Capua e della giovane Delogu. Altre Ricerche coi Soldi UE

«Nanotechnology tools to inactivate SARS-CoV-2 in patients could also be explored. In this case, nanomaterials could be used to deliver drugs to the pulmonary system to inhibit interaction between angiotensin-converting enzyme 2 (ACE2) receptors and viral S protein. Moreover, the concept of “nanoimmunity by design” can help us to design materials for immune modulation, either stimulating or suppressing the immune response, which would find applications in the context of vaccine development for SARS-CoV-2 or in counteracting the cytokine storm, respectively. In addition to disease prevention and therapeutic potential, nanotechnology has important roles in diagnostics, with potential to support the development of simple, fast, and cost-effective nanotechnology-based assays to monitor the presence of SARS-CoV-2 and related biomarkers. In summary, nanotechnology is critical in counteracting COVID-19 and will be vital when preparing for future pandemics».

Dr. Delogu herself specified with other scientists (including the avid veterinary PRO VAX Ilaria Capua) in another research published in 2020 (source 10), a few months before the experimental gene serum was put on the market.

But that is not all: «For instance, graphene oxide functionalized with amino groups (GO-NH2) induces activation of STAT1/IRF1 interferon signaling in monocytes and T cells, resulting in the production of T cell chemoattractants, and macrophage 1 (M1) 1/T-helper 1 (Th1) polarization of the immune response, with negligible toxicity».

WUHAN-GATES – 49. SARS-2 FAUCI, GRAFENE DARPA-OBAMA, VACCINI GATES-BIDEN-UE. Complotto NWO per Controllo NeuroCerebrale

6 – GRAPHENE OXIDE IN LIPID MEMBRANES

The danger to humans should not be “negligible” for Pfizer and Biontech scientists who find themselves manipulating “PF” lipid nanoparticles from ultra-secret compounds after “the toxicological properties have been not thoroughly investigated”. This sentence should be remembered in every chapter …

It was not negligible, however, in 2013 when researchers Yinfeng Li, Hongyan Yuan, Annette von dem Bussche, Megan Creighton, Robert H. Hurt, Agnes B. Kane, and Huajian Gao tried to graft graphene right into lipid cells.

VACCINI & GRAFENE – 4. “VERME ATTORCIGLIATO AI GLOBULI ROSSI”. Savigliano rilancia SOS di Campra. Studio a Palermo: “Coaguli Letali da Sieri Genici”

The research conducted by Brown University of Providence (Rhode Islands, USA) together with the Department of Mechanical Engineering of Shanghai Jiao Tong University (China) published in the specialized journal PNAS (Proceedings of the National Academy of Sciences of the United States of America) started from these premises (Source 6).

«Understanding and controlling the interaction of graphene-based materials with cell membranes is key to the development of graphene-enabled biomedical technologies and to the management of graphene health and safety issues. Very little is known about the fundamental behavior of cell membranes exposed to ultrathin 2D synthetic materials. Here we investigate the interactions of graphene and few-layer graphene (FLG) microsheets with three cell types and with model lipid bilayers by combining coarse-grained molecular dynamics (MD), all-atom MD, analytical modeling, confocal fluorescence imaging, and electron microscopic imaging».

Cellular uptake and internalization of few-layer graphene microsheets. (A–C) Confocal images of human lung epithelial cells (A and B) and mouse macrophages (C) exposed to graphene microsheets (0.5- to 25-μm lateral dimension) after 24 h and 5 h, respectively. The nuclei in A and B are visualized (blue fluorescence) with 4′,6-diamidino-2-phenylindole (DAPI). The microtubules of the lung epithelial cells (A and B) are visualized using antitubulin beta antibodies conjugated with FITC (green fluorescence), whereas the actin cytoskeleton of macrophages shown in C is visualized using rhodamine–phalloidin (red fluorescence). In unexposed lung epithelial cells (A and B, Inset), cytoplasmic microtubules (MT) form a linear network spanning across the cytoplasm. Internalized graphene flakes (yellow arrows, A and B) physically displace the linear microtubular network. In unexposed macrophages (C, Inset), filamentous actin (F) is organized into aggregates beneath the plasma membrane. Internalized graphene flakes with large lateral dimension (yellow arrow, C) induce dense aggregates of actin filaments whereas submicron graphene sheets (yellow arrowhead, C) do not disrupt the actin cytoskeleton. Transmission electron micrographs of macrophages (D) and lung epithelial cells (E) exposed to 10 ppm FLG sheets (∼800 nm in lateral dimension) for 5 h and 24 h show localization in the cytoplasm within membrane-bound vacuoles (blue Insets). Graphene microsheets inside vacuoles appear as electron-dense linear sections (D, Inset) or irregular flakes (E, Inset).

They came to these conclusions: «The penetrated portion of the membrane then propagates along the whole edge, resulting in full penetration (Movie S2). In this process, the energy barrier to penetration is overcome by local piercing at sharp corners along the nominally flat edge, and the full penetration is driven by the attractive interaction between the graphene and the tail groups of lipids once initial piercing is successful».

And then they added the disturbing final consideration: «The ability of graphene microsheets with large lateral dimension to penetrate and enter cells, documented here both experimentally and through simulation, may lead to cytoskeletal disruption, impaired cell motility, compromised epithelial barrier function, or other geometric and steric effects that deserve further study».

Wikipedia summarized a subsequent technical problem that it would take too long to mention in detail: «Multilayer graphene crystals with a thickness of 10 µm were able to perforate cell membranes in solution; a research by Brown University describes the potential toxicity of graphene: it would affect and damage human cells due to its two-dimensional nature, especially when finely fragmented».

7 – “CELL DAMAGE FROM THE SHARP EDGES OF GRAPHENE”

«The studies till date indicate that toxicity of graphene could be dependent on the shape, size, purity, post-production processing steps, oxidative state, functional groups, dispersion state, synthesis methods, route and dose of administration, and exposure times. The morphology, shape and size of graphene nanoparticles could influence their cellular uptake characteristics whereas presence of functional groups can alter their interactions with proteins, biomolecules and micronutrients. The initial starting materials and the methods used in the production of oxidized graphene can result in the presence of metallic impurities and oxidative debris in the final product, which could result in variable toxicity effects» wrote three years later scientists from the Department of Biomedical Engineering at Stony Brook University (in the city of the same name in New York state), Gaurav Lalwani, Michael D’Agati, Amit Mahmud Khan and Balaji Sitharaman (Source 7).

Graphene nanoparticles stuck in various shapes into the cell membranes of laboratory animals at Stony Brook University

«The post synthesis processing steps employed to disperse the nanoparticles in aqueous media could also influence toxicity. Reactive oxidation species mediated cell damage has been postulated as a primary cytotoxicity mechanism of graphene. Graphene sheets with sharp edges could induce direct physical damage and interact with phospholipids leading to membrane destabilization. Surface coating of graphene with several biocompatible moieties (e.g. natural polymers) can mitigate these cytotoxicity effects» we further read in the research

They also issued a serious warning through the study published in the specialized journal PMC of the US National Library of Medicine National Institutes of Health thanks to a contribution from the Wallace H. Coulter Foundation and the NIH itself: that in light of the intrigues unveiled in the first chapter of this investigation could be really suspicious …

«For all types of graphene nanoparticles, it is important to investigate and critically evaluate the potential short- and long-term health risks and toxicity hazards after acute, sub-acute and chronic exposures using in vitro and in vivo (small and large animal) models. Towards clinical translation of any graphene-based biomedical application that requires its systemic administration, formulations with high purity, dispersibility in aqueous media, and controlled physiochemical properties are highly desirable. For each of these formulations, regulatory compliance would require mapping of their chemistry, manufacturing and control (CMC) process and completing new drug (IND)-enabling preclinical studies.

Some graphene nanoparticles identified by chemist Pablo Campra in the Comirnaty vaccine (source 8) are very similar to those detected by American scientists

But in times of pandemic, all clinical trials have taken place at a rapid pace. Even with the concealment of 1,223 deaths in Pfizer’s first three months of pharmacovigilance, revealed only a year later thanks to protests with the FDA of an American association of journalists and lawyers.

Obviously, we cannot confirm that the lipid nanoparticles of the compound PF-07302048 contain graphene oxide sheets, functional for biomedical purposes in part positive and in other part very dangerous and potentially invasive that we will see in a future investigation.

WUHAN-GATES – 9. THE PROOFS: HIV inserted in SARS chimeric virus in 2007. Thanks to Australian & EU Commission Funds

But we believe we have succeeded in demonstrating that these GO grafts in lipids are not only possible but have been tested in various researches for pharmacological purposes conducted by the same GRAPHENE FLAGSHIP created by the European Commission which financed the research of the Wuhan Institute of Virology for a SARS virus. recombinant infected with HIV and who met on September 12, 2019 with the Pfizer manager to plan global immunization a few weeks before the pandemic.

The clues are serious, unambiguous, precise and consistent like those that would be enough for an honest magistrate to start arresting some second or third level manager or politician.

At this point it will be up to the Spanish chemist Pablo Campra who detected them under the electron microscope to evaluate whether this is the scientific path to follow. If the presence of this carbon allotrope were confirmed, it would be easy to understand why the “toxicological properties” of the Comirnaty vaccine “have not been thoroughly studied” by Pfizer.

Because is taking place through the gene sera “a possible alteration of human DNA in a global experiment for humanity”. Words by Walter Doerfler, luminary of Cologne genetics.

Fabio Giuseppe Carlo Carisio
© COPYRIGHT GOSPA NEWS
prohibition of reproduction without authorization 
follow Gospa News on Telegram


MAIN SOURCES

1 – Pfizer-BioNTech COVID-19 Vaccine – Safety Data Sheet 2021 ENG 

2 – FRONTIERS IN CELL AND DEVELOPMENTAL BIOLOGY – The Critical Contribution of Pseudouridine to mRNA COVID-19 Vaccines

3 – Pfzer-BioNTech Fact Sheet

4 – Pfizer-BioNTech COVID-19 Vaccine – Safety Data Sheet 2020 ITA

5  – GRAPHENE FLAGSHIP – G-IMMUNOMICS investigates the chemical recipe for biocompatible graphene

6 – PNAS – Graphene microsheets enter cells through spontaneous membrane penetration at edge asperities and corner sites

7 – PMC – Toxicology of Graphene-Based Nanomaterials

8 – RESEARCH GATE – DETECTION OF GRAPHENE IN COVID19 VACCINES

9 – NATURE COMMUNICATIONS – Graphene research

10 -ACS CHEMISTRY FOR LIFE – Toward Nanotechnology-Enabled Approaches against the COVID-19 Pandemic

GOSPA NEWS – WUHAN-GATES DOSSIER

GOSPA NEWS – COVID-19 INVESTIGATIONS

WUHAN-GATES – 50. The Italian Boss of Obama’s Coronavirus. Ukraine Laboratories Funded by former CIA Director Leon Panetta

1.223 MORTI CELATE DA PFIZER NEI PRIMI 3 MESI DI VACCINI COVID. Dossier Esplosivo ottenuto da Medici e Giornalisti Americani

BOMBSHELL: Pfizer whistleblower says vaccine ‘glows,’ contains toxic luciferase, graphene oxide compounds

 

 

 

 

(Visited 1.740 times, 1 visits today)

Fabio G.C. Carisio