“SPIKE PROTEIN more than 700 DAYS in the BLOOD of COVID VACCINATED”. Yale Study confirms Post-Vaccination Syndrome
In the cover image Akiko Iwasaki, Sterling Professor of Immunology at Yale University, and her preprint study
Yale Preprint Identifies Post-Vaccination Syndrome, Points to Lack of Recognition
by Marina Zhang – originally published by The Epoch Times
All link to previous Gospa News articles have been added in the aftermath
Researchers have identified a condition, termed post-vaccination syndrome or PVS, following COVID-19 mRNA or COVID-19 adenovirus vaccinations, according to a recent preprint from Yale University. This condition is reported in only a small fraction of the population, the researchers wrote.
PVS shares similar symptoms to long COVID, including chronic fatigue, sleep difficulties, brain fog, and nerve changes, for months to years.
What was done in the preprint study, which recognizes a new form of chronic-fatigue like syndrome, was “extremely challenging research to conduct from every aspect of research operations,” said David Putrino, one of the study researchers and director of rehabilitation innovation at the Mount Sinai Health System.
The study was led by patient demand. Research groups at Yale and Mount Sinai were approached by hundreds of people who reported significant health decline after receiving the COVID-19 vaccines, but the first challenge was funding, Putrino told The Epoch Times.
“Given the sensitivity of the topic, no one was willing to fund this work,” Putrino said. Once they used existing funds to conduct a small pilot study, the second challenge came: they had to prove PVS patients weren’t suffering from long COVID.
The study found, like for long COVID, PVS patients often had persisting spike proteins, with some patients continuing to have spike protein in the blood at 700 days after their last vaccination.
PVS patients would also tend to have co-infections with other viruses like Epstein Barr and herpes. Unlike long COVID patients, PVS patients had exhausted or inactive T cells—cells that are involved in killing cancer and infected cells. “The subtle changes in T cells were not the same ones we see in long COVID,” Iwasaki said, adding that the two conditions are not the same.
While long COVID happens after infection with SARS-CoV-2, “PVS happens shortly after receiving COVID vaccines and is not caused by the infection,” Iwasaki said. “Vaccines can reduce the risk of developing long COVID,” Iwasaki said.
“Our study on PVS is based on a small number of people and requires a larger study to confirm the findings.”
Immune System Changes
The small preliminary study evaluated 42 patients with PVS who received an initial COVID-19 vaccination, half of which had a prior COVID-19 infection while the other half did not. These patients were compared against 22 healthy controls who did not experience PVS after getting COVID-19 vaccinations.
The researchers also found that patients with PVS had autoantibodies. While antibodies help fight off foreign infections, autoantibodies attack normal self-tissues.
The researchers found that the autoantibodies could attack 65 different types of human markers.
They also highlighted two types of autoantibodies that appeared to be more prevalent in PVS patient samples. One type is anti-nucleosome autoantibodies, which is implicated in lupus, and another is anti-AQP4, which is implicated in neuromyelitis optica, a nervous system autoimmune disease.
PVS patients had low levels of antibodies to spike proteins compared with healthy controls, which the researchers linked to their discontinuance of COVID-19 booster vaccinations after getting PVS. The spike protein is what the SARS-CoV-2 virus uses to cause infection.
The mRNA and adenovirus COVID-19 vaccines also induce the body to make spike protein so that the body would be able to recognize the spike protein as foreign and attack it.
Like long COVID patients, PVS patients continued to have persistent spike proteins in their blood. These PVS patients had higher levels of spike protein compared to long COVID patients. The authors detected spike protein in blood samples ranging from 26 to 709 days, or the extent of study.
“Why persistent spike antigen fails to elicit an antibody response, and what the source of persistent spike in circulation is, requires further investigation,” the authors wrote.
Iwasaki said it was surprising to find circulating spike protein at such a “late time point.” “We don’t know if the level of spike protein is causing the chronic symptoms, because there were other participants with PVS who didn’t have any measurable spike protein. But it could be one mechanism underlying this syndrome.”
What It Means
Prior to the Yale study, there have been doctors discussing this post-vaccination syndrome, which they have observed to be very similar to chronic fatigue syndrome. However, this idea remains controversial.
by Marina Zhang – originally published by The Epoch Times
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