WUHAN-GATES – 2. HIV TRACKS INSIDE CORONAVIRUS “BIO-WEAPON”. Proof by Indian Research Misteriously Concealed
by Fabio Giuseppe Carlo Carisio
«The finding of 4 unique inserts in the 2019-nCoV, all of which have identity /similarity to amino acid residues in key structural proteins of HIV-1 is unlikely to be fortuitous in nature. This work provides yet unknown insights on 2019-nCoV and sheds light on the evolution and pathogenicity of this virus with important implications for diagnosis of this virus».
These two sentences could have marked the beginning of an in-depth research on the new strain of CoronaVirus which until April 14 caused more than 117 thousand deaths worldwide with the SARS-Cov-2 pandemic, so named for its correlations to Respiratory Syndrome Acute severe in 2003 (813 deaths only).
But as those words also opened the door to the conspiracy theory of bacteriological weapon insinuating that this virus had been produced in the laboratory, the disturbing research (source 1) has been hidden by the scientific community. This happened although CoVid-19 is still without cure, without exact diagnosis, without ascertained causal links of lethality 3 months after its discovery in Wuhan, in December 2019.
For this reason, after highlighting in the previous 11 reports all the serious, precise and concordant indications sufficient to describe CoVid-19 as a bio-weapon, we went to recover, with no little effort, the study of the authoritative team of scientists from the Kusuma School of Biological Sciences of the Indian Institute of Technology Delhi (IIT Delhi), as hoped in an interview to the newspapers by the Italian specialist Maria Rita Gismondo, director of the Laboratory of Clinical Microbiology, Virology and Diagnostics of the Bio-emergencies of the Sacco Hospital in Milan.
The evidence of that Indian research, elaborated with chemical graphs and every scrupulous technological device, remained in the availability of world researchers only for 24 hours, from 30 January to 1 February 2020.
Then it was inexplicably removed by the authors themselves, probably put under tremendous pressure from the world of medicine and biology, and today it can only be found on two other medical science websites. In one of them on each page. the word “retired” stands out in English. Partly crediting its scientific foundation, however, is the study carried out to deny its conclusions which, in fact, in turn confirms the existence of some traces similar to those of HIV in the Covid-19 genome.
Although the study has been “hidden” in the last three months, the health systems of many countries of the world have focused on antivirals and precisely on retroviral anti-HIV drugs, the AIDS virus, to identify the most effective cure to prevent lethals pulmonary interstitial fungal infections.
If further recent studies in China and Italy, following the very few autopsies carried out, have revealed as a probable cause of death also cardiovascular thrombosis capable of triggering massive pulmonary embolism (we will talk about it in another article), in the last weeks the experiments with chloroquine or hidroxichloroquine associated with anti-AIDS drugs have obtained results of different but confirmed efficacy.
ITALIAN HEALTHCARE IGNORE THE LINKS BETWEEN COVID-19 AND HIV
This occurred in the context of research that gropes in the darkness of the complexity of the virus, of which various different genotypes have already been ascertained, capable of attacking the infected in a different way, as also emerges from the findings on mortality from one country to another.
But despite this, the Indian study was censored by the biochemical community demonstrating a far from scientific approach given the still very mysterious characteristics of CoVid-19. A striking example emerges from the pages of the Istituto Superiore della Sanità in Rome regarding the use of chloroquine.
«This drug belongs to the category of HIV protease inhibitors, an enzyme essential for the final cut of the various viral components. The fact that it had later been shown to inhibit a SARS virus protease was also quite amazing, because the HIV and coronavirus proteases do not share structural similarities»
«The idea of using chloroquine in combination with lopinavir and returnavir against SARS coronavirus was first launched by Andrea Savarino in 2005, based on observations he previously made in cells infected with a virus from a different family (HIV )».
The discovery is disturbing.
At the date of the release of the press release in the press office section, on 18 February 2020, the Italian ISS ignored (or didn’t consider relevant) the research led by the Indian biochemist Bishwajit Kundu, awarded for a study on human prion proteins by the National Academy of Sciences of the USA, and his colleague James Gomes, who graduated in Chemical Engineering at Jadavpur University and in Master of Science at Tulane University in New Orleans, who in the past has also obtained the prestigious Sigma Xi recognition for scientific research.
Well, despite this, even Professor Anthony Fauci, president of the American National Institute of Allergy and Infectious Diseases, would have contacted his friend and colleague Enrico Garaci, director of the Italian Superior Health Institute for years, to get information on how the Italy was approaching the disease.
THE 4 AIDS’ AMINO ACIDS INSIDE CORONAVIRUS
«The evolution of 2019-nCoV remains elusive. We found 4 insertions in the spike glycoprotein (S) which are unique to the 2019-nCoV and are not present in other coronaviruses. Importantly, amino acid residues in all the 4 inserts have identity or similarity to those in the HIV-1 gp120 or HIV-1 Gag. Interestingly, despite the inserts being discontinuous on the primary amino acid sequence, 3D-modelling of the 2019-nCoV suggests that they converge to constitute the receptor binding site».
The two scientists wrote in the abstract of their research (1) supported by some students of the renowned Kusuma School of Biology but then mysteriously withdrawn
Their discovery was liquidated with the facility of a Facebook post by the Italian Enrico Bucci, adjunct professor at the Temple University of Philadelphia: «Two sequences are typical of bat coronavirus, while of the remaining two only one is really preserved with HIV, but it is only 6AA long, which means that the data is purely random (2)».
Bucci, who became famous for the blog on FB Criminal “Balle (lies)” and for his book Bad Scientists rather than for his research, founded three biopharmaceutical companies, assuming in 2008 the scientific direction of the BioIndustry Park of Canavese (Turin).
That’s a specialist center of European excellence between companies and industries in the medical sector where Advanced Accelerator Applications srl stands out, a company controlled by the Swiss big-pharma Novartis and European leader in the production and marketing of radiopharmaceuticals obtained from radioactive elements (such as rhenium, holmium or lutetium) in the field of Molecular Nuclear Diagnostics (MND).
The Swiss multinational is now engaged in research for the CoronaVirus vaccine but according to the declarations made to Corriere (3) by its manager Pasquale Frega, CEO of Novartis Italia, it is already ready “to donate hydroxychloroquine to the global fight against Covid” as soon as he gets the ok from AIFA (Italian Medicines Agency).
On the other hand, this big-pharma has a bad experience to make Italy forget: «The Italian Medicines Agency has banned the sale of two batches of the Fluad flu vaccine, from the Novartis pharmaceutical company, after the suspected deaths of three people who had just been given it» Focus magazine wrote on 28 November 2014 (4). Even the EMA (European Midicines Agency) suspended it when the dead became 11 but later “exonerated” the drug thus allowing it to be put back on the market.
The criticism of the pharmaceutical entrepreneur Bucci to Indian research, however, was emphasized by Open, Italian online newspaper which became famous for celebrating the virtues of the Hungarian-American plutarch George Soros who leads the New York Open Society with the similar name, engaged in the “philanthropy” of US and European Democratic politicians as highlighted by the famous Soros List in Brussels.
THE WUHAN’S SUPERVIRUS AND HIV TRACKS IN COVID-19
For simple and necessary “PLOT-LOGY” (analys of plots, which differs from “imaginary plotism” for his accurate scientific foundations), we had found that the military laboratories of the US Pentagon for the production of bacteriological weapons including bio-genetic ones had increased with the help of US government agencies DTRA, DARPA, USAID and the infamous CIA in Ukraine and Georgia just after the colorful revolutions funded by Soros.
For the same reasons of honest research of scientific truths we have also highlighted that the extremely dangerous super-virus modeled on that of SARS was created in the BSL 4 laboratory in Wuhan, which ended up in the sight of any speculation on the bio-weapon theory of the American expert Francis Boyle.
That disturbing experimentation of a “chimeric” pathogen, that is artificially created with genome editing but not existing in nature, was conducted thanks to USAID funding during the administration of Barack Obama, exponent of the Democraic Party financed both by Soros and by pandemic prophet Bill Gates.
This happened in the period 2013-2017 in which the former US president was supported in the National Security policies of the White House by the deputy Adviser Avril Haines, former CIA deputy director, bio-arms expert and protagonist of the suspected exercise on the CoronaVirus pandemic called Event 201 organized in New York with the financing of the Bill & Melinda Gates foundation.
Obviously, these are just incredible coincidences!
Such as the presence of the four HIV inserts in CoVid-19 discovered by Indian scientists and then hidden from the whole world with the help of a scientific study that considered these traces to be random.
«A recent informally presented report, however, showed that 2019-nCoV had four insertions in the spike glycoprotein gene that is critical for the virus to enter the target cells when compared to other coronaviruses » wrote the research team (source 5) led by two Chinese scientists referring to the famous “killer” protein S.
Spike in Covid-19 promotes viral propagation in the human respiratory tract in the same dramatic way as the chimeric supervirus experimented on mice in Wuhan.
«It was claimed that these inserts were either identical or similar to the motifs in the highly variable (V) regions (V1, V4 and V5) in the envelope glycoprotein or in the Gag protein of some unique HIV-1 strains from three different countries (Thailand, Kenya and India). Together with the structure modelling analysis, the authors speculated that these motif insertions sharing similarity with HIV-1 proteins could provide an enhanced affinity towards host cell receptors and increase the range of host cells of 2019-nCoV. This study implies that 2019-nCoV might be generated by gaining gene fragments from the HIV-1 genome» we can still read in the introduction to the scientific dossier contesting the results of the Indian study..
This hypothesis, if ascertained, would confirm the theory that this new CoronaVirus would have been elaborated in the laboratory exactly as it happened for the “chimeric” SHC014 (also connected to SARS but different for various nucleids from the viral strain of the current pandemic) built, as mentioned above, in the maximum bio-safety facilities of the Wuhan Virology Center and Chapel Hill of North Carolina University.
That supervirus was created in 2015 as part of the project funded not only by the government agency USAID (often the economic instrument of the Central Intelligence Agency) but also by the NGO EcoHealthAlliance of New York, supported in turn by giants such as Johnson & Johonson but also by the most prestigious Pharmacy University of the Kingdom of Saudi Arabia (see WuhanGate reportage – 1).
What does the group of Chinese scientists who analyzed the Indian study claim??
«However, while the 100% match between the insertion 1 and 2 sequences and the HIV sequences were found in 19 entries, the matches between the insertion 3 and 4 sequences and HIV-1 sequences were rather poor (from 42% to 88%). Moreover, the insertion 4 sequence ambiguously hit multiple different genes (gag, pol and env) in the HIV-1 genome, suggesting that similarities (as low as 42%) between them are too low to be reliable. ».
THE BRITISH SCHOOL CHINESE REFUTE THE INDIANS
The research by Feng Gao, a graduate of Cambridge (Uk) and now assistant of the Department of Physics, Chemistry and Biology (IFM) of the University of Linkoping, Sweden, and his colleague Xiaojun Li of the Institute of Asian Research at the University of British Columbia in Vancouver (Canada), also published on the NHI website, the US National Institute of Health, therefore confirms the existence of traces of HIV-1 but not for all insertions.
«Sequences that completely match the insertion 3 and 4 sequences were not found in any HIV-1 sequences. This clearly shows that these insertioin sequences are widely present in living organisms including viruses, but not HIV-1 specific. All these regions in HIV-1 envelope glycoprotein are highly variable with many large insertions and deletions, indicating that they are not essential for biological functions of HIV-1 envelope glycoprotein. The detection of completely matched sequences of 1 and 2 insertions in only a few HIV-1 strains demonstrated that four insertions are very rare or not present among tens of thousands of natural HIV-1 sequences. This also explains why four insertion homolog sequences could only be independently found in different HIV-1 genomes. Because of their poor identities to and rareness in the HIV-1 sequences, HIV-1 could not be the source for those insertion sequences in the 2019-nCoV genome».
The “rare” presence is sufficient for the two British-based Chinese scientists to close the case without further investigation into that strange “contamination” between viruses. The research does not highlight how many probabilities, perhaps infinitesimal, exist of such a hypothetical natural combination …
The conclusions of the Indian researchers of the Biological School of Kusuma were very different: «Our results highlight an astonishing relation between the gp120 and Gag protein of HIV, with 2019-nCoV spike glycoprotein. These proteins are critical for the viruses to identify and latch on to their host cells and for viral assembly (Beniac et al., 2006). Since surface proteins are responsible for host tropism, changes in these proteins imply a change in host specificity of the virus».
Indian research points out: «Due to the presence of gp120 motifs in 2019-nCoV spike glycoprotein at its binding domain, we propose that these motif insertions could have provided an enhanced affinity towards host cell receptors. Further, this structural change might have also increased the range of host cells that 2019-nCoV can infect. To the best of our knowledge, the function of these motifs is still not clear in HIV and need to be explored. The exchange of genetic material among the viruses is well known and such critical exchange highlights the risk and the need to investigate the relations between seemingly unrelated virus families».
In simpler words, according to the study conducted by researchers from New Delhi, these “inserts” would have made the new viral strain of SARS-2 more aggressive and contagious. The discovery could therefore explain the difference in morbidity and mortality compared to the SARS of 2003. But as it could confirm the thesis of a virus built with biochemical engineering and therefore a bacteriological weapon it is better not to investigate the surprising results …
«To our surprise, all the 4 inserts in the 2019-nCoV mapped to short segments of amino acids in the HIV-1 gp120 and Gag among all annotated virus proteins in the NCBI database. This uncanny similarity of novel inserts in the 2019- nCoV spike protein to HIV-1 gp120 and Gag is unlikely to be fortuitous. Further, 3D modelling suggests that atleast 3 of the unique inserts which are non-contiguous in the primary protein sequence of the 2019-nCoV spike glycoprotein converge to constitute the key components of the receptor binding site. Of note, all the 4 inserts have pI values of around 10 that may facilitate virus-host interactions. Taken together, our findings suggest unconventional evolution of 2019-nCoV that warrants further investigation. Our work highlights novel evolutionary aspects of the 2019-nCoV and has implications on the pathogenesis and diagnosis of this virus» wrote the team led by Bishwajit Kundu and James Gomes.
THE MODELED KILLER PROTEIN AND THE LETHAL GENOTYPE
The investigation of their colleagues instead would have hurriedly ruled out any consequences. The withdrawal of the study has silenced Kusuma researchers despite having noticed the same suspicious modeling highlighted by the first Chinese scientists who had discovered the genetic trace of the new CoronaVirus.
On January 21, in fact, three scholars from the Chinese Academy of Sciences published a joint article in English in the journal “Science China Life Sciences”. It was Pei Hao, researcher from the Shanghai Pasteur Institute and the Chinese Academy of Sciences, Wu Zhong, researcher from the National Engineering Research Center for Emerging Drugs, Academy of Military Medical Sciences and Xuan Li, researcher from the Key Laboratory of Synthetic Biology, CAS Center for Excellence in Molecular Plant Sciences.
«The researchers were shocked when they compared the SARS “S” protein with the Wuhan CoV “S” protein and found that it does not alter the structural composition of the virus even if four amino acids have been replaced» commented the leaders of the Chinese Communist Party accusing the US to have built and spread a bacteriological weapon and highlighting the same criticality of four elements apparently masked in it.
To this was added the even more sensational discovery of two different genotypes of the virus, among which the most virulent for rapid spread and lethality defined “L ‘by scientists from six different Chinese academic laboratories in Beijing and Shanghai.
«It is currently unclear how the L type specifically evolved from the S type during the development of SARS-CoV-2. However, we found that the sequence of viruses isolated from one patient that lived in the United States on January 21 had the genotype Y (C or T) at both positions 8,782 and 28,144, differing
from the general trend of having either C or T. Although novel mutations could lead to this result, the most parsimonious explanation is that this patient may have been infected by both the L and S types».
In their study it is hypothesized that the greater aggression of the “L” type, present in 70% of the 103 isolated viral genotypes but even in 96% of the 27 in Wuhan compared to the remaining ones in other areas outside the outbreak city, could have been caused by the interventions therapeutic. But these Chinese scientists do not even remotely ponder the hypothesis of its construction in the laboratory suggested by the surprising modeling of the killer protein Spike.
According to research on the Cortellis Clarivate Analytics epidemic, the dangerousness of the virus lies precisely in these combinations. Because although according to some studies the “S” type favors an immune reaction suitable to defeat the “L” one, «Coronaviruses are capable of adapting quickly to new hosts through the processes of genetic recombination and mutation in vivo».
«Point mutations alone are not sufficient to create a new virus, however; this can only occur when the same host is simultaneously infected with two coronavirus strains, enabling recombination (6)».
INDIAN RESEARCH USEFUL FOR PHARMACY
In this apocalyptic and enigmatic scenario for biologists themselves, the intuition of a connection between CoVid-19 and HIV of Indian research, which later became “taboo” for the whole world, has however proved to be invaluable for some medical experiments.
Even the most disappointing studies have positive notes. The one coordinated by Professor Bin Cao of the China-Japan Friendship Hospital & Capital Medical University of Beijing (7), out of 199 people with Covid19, showed no “significant benefits” among the 99 patients who underwent antiviral therapy against AIDS for 28 days Lopinavir / Ritonavir in addition to standard care. But it is true that the mortality rate in patients treated with the anti-HIV combination has fallen by 5.8 percentage points, from 25 to 19.2%..
«There is anecdotal evidence to suggest that anti-HIV drugs may be effective. Thai doctors gave lopinavir and ritonavir in combination with a flu drug to a Chinese coronavirus patient, who tested negative for the virus within two days. In Japan, a patient from Wuhan, China, was treated with just the two HIV drugs and her fever subsided within five days of being admitted to the hospital. And a report in the journal JAMA in March 2020 showed that three of five patients recovered after being treated with the same two drugs» reports the website of AMFAR, an organization focused on AIDS research (8).
«While the entire world is grappling with ways and means to contain and cure coronavirus, Indian doctors have succeeded in curing coronavirus patients with a mix of HIV, swine flu, and Malaria, drugs. This combination was recently used for the first time to treat the coronavirus disease amid a growing number of cases in India» wrote K. Venkateshwar Rao on InsideOver (9).
The treatment was tested on a couple of Italian tourists. Doctors from Sawai Man Singh (SMS) hospital, Jaipur initially treated her with a combination of two drugs useful in the treatment of HIV together with chloroquine (anti-malaria) and oselamiivr (against swine flu) authorized with “limited use”. ”By the Drug Controller General of India (DCGI) at the request of the Indian Council of Medical Research (ICMR).
The head of the medical college, Dr Sudhir Bhandari said:: «We provided her treatment following standard protocol and now she has tested negative for the disease, which is a major achievement for SMS Hospital doctors.” ».
To these reports is added the position of the World Health Organization which on its official website reports: «Several studies have suggested that patients infected with the virus causing COVID-19, and the related coronavirus infections (SARS-CoV and MERS-CoV) had good clinical outcomes, with almost all cases recovering fully. In some cases, patients were given an antiretroviral drug: lopinavir boosted with ritonavir (LPV/r). These studies were mostly carried out in HIV-negative individuals (10)».
THE BEIJING CENSORSHIP ON COVID RESEARCH
We have cited these examples not only to highlight a glimpse into the treatments, destined to be revolutionized again with the adoption of heparin, a powerful anticoagulant, for the recent discovery of a connection between the virus and lethal cases of thrombosis.
But above all to highlight how Indian preliminary research on the correlations between CoVid-19 and HIV, however uncomfortable in reference to the theory of insertions made with biochemical engineering by laboratories as for a bacteriological weapon, should be absolutely taken into strong consideration by the science.
Since the deaths in the US have risen to 23 thousand, dramatically exceeding only 3,600 in the Chinese province of Hubei, China has returned to the target of the accusations of the American President Donal Trump and in response has imposed censorship on the studies on SARS-Cov- 2.
A directive «was launched by the Department of Technology and Sciences of the Ministry of Education and provides that the ‘papers’ relating to the origins of the pandemic are initially examined by academic commissions within the universities and subsequently sent to the ministry, which will forward material to a task force. Only the go-ahead from this body will make it possible to proceed with the publication of the studies» writes the Italian Adnkronos agency (11), reporting a CNN report left without Beijing’s response..
In the previous report on the mysterious international intrigue of Wuhangate behind the creation of the supervirus, the perfect prototype of a bio-weapon, we saw the spectrum of a Deep State of interests between finance, big pharma, politics, intelligence that the US administration of Barack Obama went all the way to China and Saudi Arabia.
In the next we will try to shed light on the mysterious death of a scientist who was working on both a SARS vaccine and one for HIV. His untimely demise becomes highly suspect in the light of the Indian search. And even more in relation to the death of two other Chinese scientists who witnessed the Wuhan massacre and the arrests for trafficking vials with top secret biological material between the US and China.
Fabio Giuseppe Carlo Carisio
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